Cache Hierarchy-Aware Query Mapping on Emerging Multicore Architectures

One of the important characteristics of emerging multicores/manycores is the existence of 'shared on-chip caches,' through which different threads/processes can share data (help each other) or displace each other's data (hurt each other). Most of current commercial multicore systems on the market have on-chip cache hierarchies with multiple layers (typically, in the form of L1, L2 and L3, the last two being either fully or partially shared). In the context of database workloads, exploiting full potential of these caches can be critical. Motivated by this observation, our main contribution in this work is to present and experimentally evaluate a cache hierarchy-aware query mapping scheme targeting workloads that consist of batch queries to be executed on emerging multicores. Our proposed scheme distributes a given batch of queries across the cores of a target multicore architecture based on the affinity relations among the queries. The primary goal behind this scheme is to maximize the utilization of the underlying on-chip cache hierarchy while keeping the load nearly balanced across domain affinities. Each domain affinity in this context corresponds to a cache structure bounded by a particular level of the cache hierarchy. A graph partitioning-based method is employed to distribute queries across cores, and an integer linear programming (ILP) formulation is used to address locality and load balancing concerns. We evaluate our scheme using the TPC-H benchmarks on an Intel Xeon based multicore. Our solution achieves up to 25 percent improvement in individual query execution times and 15-19 percent improvement in throughput over the default Linux-based process scheduler. © 1968-2012 IEEE

Temporal Trends in the Epidemiology of HIV in Turkey

Objective: The aim of this study was to analyze the temporal trends of HIV epidemiology in Turkey from 2011 to 2016.Methods: Thirty-four teams from 28 centers at 17 different cities participated in this retrospective study. Participating centers were asked to complete a structured form containing questions about epidemiologic, demographic and clinical characteristics of patients presented with new HIV diagnosis between 2011 and 2016. Demographic data from all centers (complete or partial) were included in the analyses. For the cascade of care analysis, 15 centers that provided full data from 2011 to 2016 were included. Overall and annual distributions of the data were calculated as percentages and the Chi square test was used to determine temporal changes.Results: A total of 2,953 patients between 2011 and 2016 were included. Overall male to female ratio was 5:1 with a significant increase in the number of male cases from 2011 to 2016 (p500 cells/mm(3) while 46.7% presented with a CD4 T cell count of <350 cells/mm(3). Among newly diagnosed cases, 79% were retained in care, and all such cases initiated ART with 73% achieving viral suppression after six months of antiretroviral therapy.Conclusion: The epidemiologic profile of HIV infected individuals is changing rapidly in Turkey with an increasing trend in the number of newly diagnosed people disclosing themselves as MSM. New diagnoses were mostly at a young age. The late diagnosis was found to be a challenging issue. Despite the unavailability of data for the first 90, Turkey is close to the last two steps of 90-90-90 targets.C1 [Erdinc, F. S.; Hatipoglu, C. A.] Ankara Numune Training & Res Hosp, Infect Dis & Clin Microbiol, Ankara, Turkey.[Dokuzoguz, B.; Inkaya, A. C.] Ankara Numune Training & Researh Hosp, Infect Dis & Clin Microbiol, Ankara, Turkey.[Unal, S.] Hacettepe Univ Hastaneleri, Dept Infect Dis & Clin Microbiol, Ankara, Turkey.[Komur, S.] Cukurova Univ, Dept Infect Dis & Clin Microbiol, Adana, Turkey.[Inan, D.] Akdeniz Univ, Dept Infect Dis & Clin Microbiol, Antalya, Turkey.[Karaoglan, I] Gaziantep Univ, Dept Infect Dis & Clin Microbiol, Gaziantep, Turkey.[Deveci, A.] Ondokuz Mayis Univ, Dept Infect Dis & Clin Microbiol, Samsun, Turkey.[Celen, M. K.] Dicle Univ, Dept Infect Dis & Clin Microbiol, Diyarbakir, Turkey.[Kose, S.] Izmir Tepecik Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Izmir, Turkey.[Erben, N.] Eskisehir Osmangazi Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Eskisehir, Turkey.[Senturk, G. C.] Diskapi Yildirim Beyazit Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Ankara, Turkey.[Heper, Y.; Yilmaz, E.; Kazak, E.] Uludag Univ, Dept Infect Dis & Clin Microbiol, Bursa, Turkey.[Kutlu, S. S.] Pamukkale Univ, Dept Infect Dis & Clin Microbiol, Denizli, Turkey.[Sumer, S.] Selcuk Univ, Dept Infect Dis & Clin Microbiol, Konya, Turkey.[Kandemir, B.] Necmettin Erbakan Univ, Meram Med Fac Hosp, Dept Infect Dis & Clin Microbiol, Konya, Turkey.[Sirmatel, F.] Abant Izzet Baysal Univ, Dept Infect Dis & Clin Microbiol, Bolu, Turkey.[Bayindir, Y.; Ersoy, Y.; Yetkin, F.] Inonu Univ, Dept Infect Dis & Clin Microbiol, Malatya, Turkey.[Yildirmak, M. T.] Okmeydani Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey.[Kayaaslan, B.] Yildirim Beyazit Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Ankara, Turkey.[Ozden, K.] Ataturk Univ, Dept Infect Dis & Clin Microbiol, Erzurum, Turkey.[Sener, A.] Canakkale Onsekiz Mart Univ, Dept Infect Dis & Clin Microbiol, Canakkale, Turkey.[Kara, A.] Hacettepe Univ, Dept Infect Dis, Ihsan Dogramaci Childrens Hosp, Ankara, Turkey.[Gunal, O.] Samsun Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Samsun, Turkey.[Birengel, S.] Ankara Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Ankara, Turkey.[Akbulut, A.] Firat Univ, Dept Infect Dis & Clin Microbiol, Elazig, Turkey.[Cuvalci, N. O.] Antalya Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Antalya, Turkey.[Sargin, F.] Medeniyet Univ, Dept Infect Dis & Clin Microbiol, Goztepe Training & Res Hosp, Istanbul, Turkey.[Pullukcu, H.; Gokengin, D.] Ege Univ, Dept Infect Dis & Clin Microbiol, Izmir, Turkey

Domestication of the Triticeae in the Fertile Crescent

WOS: 000268721700003About 12,000 years ago, humans began the transition from hunter-gathering to a sedentary, agriculture-based society. From its origins ill the Fertile Crescent, farming expanded throughout Europe, Asia and Africa, together with various domesticated plants and animals. Where, how and why agriculture originated is still debated. Progress has been made in Understanding plant domestication in the last few years. New insights were obtained mainly due to (I) the use of comprehensive germplasm collections covering the whole distribution area for each species; (II) the comparison of many wild and domesticated accessions for each species; (III) the identification of the wild progenitor in the wild gene pool and its comparison with domesticate descendants (IV) the use of molecular fingerprinting techniques at many loci and the access to new generation high-throughput sequencing technologies; (V) the identification and cloning of genes involved in domestication, and (VI) excavation campaigns. This chapter reviews the recent knowledge on wheat, barley and rye domestication in the Fertile Crescent and covers several issues concerning the molecular knowledge of the effects induced by domestication and breeding of these crops